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KMID : 0361020100530050320
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Korean Journal of Otolaryngology - Head and Neck Surgery
2010 Volume.53 No. 5 p.320 ~ p.323
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A Case of Aggressive Local Recurrence of Metastasizing Pleomorphic Adenoma with Multiple Lung Metastases
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Cho Young-Joo
Yang Yun-Su
Lee Eun-Jung
Hong Ki-Hwan
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Abstract
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Metastasizing pleomorphic adenoma is a rare condition of metastasis from a histologically benign salivary gland tumor. It usually occurs after multiple local recurrences, between 3 to 52 years after the occurrence of the primary lesion. No histologic or molecular parameters exist at the present time that could predict the development of metastasis in these neoplasms. Also, there is no definite treatment protocol available in cases of widespread metastasis. We report a case of metastasizing pleomorphic adenoma presenting with aggressive recurrence and multiple bilateral lung metastases that resulted despite surgery and chemotherapy. Clinical aspects of this disease is discussed.
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KEYWORD
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Pleomorphic adenoma, Metastasis, Neoplasm recurrence, Local
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